Table 1.
Characteristics of osteosarcoma patients in study cohort.
| Factor | All patients | IMPDH2 expression | HPRT expression | ||||
|---|---|---|---|---|---|---|---|
| Low (IRS ≤ 8) | High (IRS > 8) | P value | Low (IRS ≤ 2) | High (IRS > 2) | P value | ||
| Age at diagnosis (years) | |||||||
| ≤ 15 | 65 | 37 (57%) | 28 (43%) | > 0.999 | 19 (29%) | 46 (71%) | 0.220 |
| > 15 | 62 | 36 (58%) | 26 (42%) | 12 (19%) | 50 (81%) | ||
| Gender | |||||||
| Male | 68 | 35 (52%) | 33 (48%) | 0.154 | 18 (26%) | 50 (74%) | 0.680 |
| Female | 59 | 38 (64%) | 21 (36%) | 13 (22%) | 46 (78%) | ||
| Enneking stage | |||||||
| IIB | 72 | 41 (57%) | 31 (43%) | 0.545 | 13 (18%) | 59 (82%) | 0.023 |
| III | 39 | 25 (64%) | 14 (36%) | 15 (38%) | 24 (62%) | ||
| Site | |||||||
| Extremities | 104 | 61 (59%) | 43 (41%) | > 0.999 | 14 (33%) | 80 (77%) | 0.750 |
| Axial | 15 | 9 (60%) | 6 (40%) | 4 (27%) | 11 (73%) | ||
| Metastasis | |||||||
| No | 36 | 21 (58%) | 15 (42%) | 0.742* | 4 (11%) | 32 (89%) | 0.024* |
| At follow-up | 36 | 20 (56%) | 16 (44%) | 9 (25%) | 27 (75%) | ||
| At diagnosis | 39 | 25 (64%) | 14 (36%) | 15 (38%) | 24 (62%) | ||
P values were calculated with Fisher’s exact test.
*P values were calculated with Chi-square test.