Table 2.

Patient survival analysis (N = 119).

Factor	Patients	Events (death)	Median survival (months)	P value (Log rank test)
Age at diagnosis (years)
≤ 15	58	40	20.5	0.384
> 15	61	44	17.0
Gender
Male	64	50	17.7	0.258
Female	55	34	20.5
Enneking stage
IIB	71	42	27.1	0.001
III	38	32	12.5
Site
Extremities	102	70	20.6	0.183
Axial	13	10	12.7
Metastasis
No	36	12	Undefined	< 0.0001
Yes	73	62	15.4
Treatment
Completed treatment	74	44	27.8	< 0.0001
Not completed treatment	45	40	9.0
IMPDH2 expression
Low (IRS ≤ 8)	70	53	15.5	0.119
High (IRS > 8)	49	31	21.4
HPRT expression
Low (IRS ≤ 2)	30	26	13.6	0.0196
High (IRS > 2)	89	58	21.9
IMPDH2/HPRT ratio
Low IMPDH2/HPRT	81	52	24.4	0.040
High IMPDH2/HPRT	38	32	15.8

P values were calculated using the log-rank test. P values < 0.05 shown in bold.