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Multivariate analysis of metastasis-free survival in osteosarcoma patients and HPRT expression in post-chemotherapy tissues (n = 20).
| Factor | Overall survival | |
|---|---|---|
| HR (95% CI) | P value | |
| Age at diagnosis (years) | ||
| ≤ 15 | 1.00 | – |
| > 15 | 1.69 (0.47–6.11) | 0.423 |
| Gender | ||
| Male | 1.00 | – |
| Female | 0.24 (0.06–0.95) | 0.042 |
| Site | ||
| Extremities | 1.00 | – |
| Axial | 0.58 (0.12–2.96) | 0.517 |
| HPRT expression | ||
| Low (IRS ≤ 6) | 1.00 | – |
| High (IRS > 6) | 1.07 (0.32–3.55) | 0.909 |
