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. 2021 May 25;11:10887. doi: 10.1038/s41598-021-90456-4

Table 9.

Multivariate analysis of metastasis-free survival in osteosarcoma patients and IMPDH2/HPRT ratio in post-chemotherapy tissues (n = 20).

Factor Overall survival
HR (95% CI) P value
Age at diagnosis (years)
 ≤ 15 1.00
 > 15 2.22 (0.56–8.84) 0.257
Gender
Male 1.00
Female 0.25 (0.06–1.00) 0.051
Site
Extremities 1.00
Axial 0.45 (0.08–2.38) 0.348
IMPDH2/HPRT ratio
Low IMPDH2/HPRT 1.00
High IMPDH2/HPRT 0.47 (0.08–2.55) 0.380