Table 2.
Top 5 causative drug categories responsible for acute and chronic SOCs in SJS/TEN patients.
| Name of causative drugs | No. of patients (%) |
|---|---|
| Acute SOCs | N = 67 |
| Antiepileptics | 15 (22.4) |
| Phenytoin | 2 (3.0) |
| Carbamazepine | 4 (6.0) |
| Oxcarbazepine | 5 (7.5) |
| Lamotrigine | 2 (3.0) |
| Zonisamide | 2 (3.0) |
| Antibiotics | 12 (17.9) |
| Cephalexin | 1 (1.5) |
| Cefuroxime | 1 (1.5) |
| Ceftazidime | 1 (1.5) |
| Ceftriaxone | 1 (1.5) |
| Norfloxacin | 1 (1.5) |
| Levofloxacin | 1 (1.5) |
| Moxifloxacin | 1 (1.5) |
| Amoxicillin | 3 (4.5) |
| Vancomycin | 2 (3.0) |
| Allopurinol | 8 (11.9) |
| NSAIDs | 7 (10.4) |
| Diclofenac | 3 (4.5) |
| Ibuprofen | 1 (1.5) |
| Mefenamic acid | 3 (4.5) |
| Sulfa drugs | 6 (9.0) |
| Sulfasalazine | 3 (4.5) |
| Sulfonamide | 3 (4.5) |
| Miscellaneous | 19 (28.4) |
| Chronic SOCs | N = 9 |
| NSAIDs | 4 (44.4) |
| Diclofenac | 2 (22.2) |
| Mefenamic acid | 1 (11.1) |
| Cold medicine | 19 (11.1) |
| Anti-epileptics | 2 (22.2) |
| Carbamazepine | 1 (11.1) |
| Lamotrigine | 1 (11.1) |
| Antibiotics | |
| Cefuroxime | 1 (11.1) |
| Sulfa drugs | |
| Sulfasalazine | 1 (11.1) |
| Tenofovir | 1 (11.1) |
SOCs, Severe ocular complications.
NSAIDs, Non-steroidal anti-inflammatory drugs.