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. 2021 May 12;12:669750. doi: 10.3389/fimmu.2021.669750

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Copyright © 2021 Guo, Tan, Huai, Wang, Shao, Zhang, Yang, Li, Xue, Gao and He

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consensus clustering identified two ESCC patient clusters and their relationship with clinicopathological parameters. (A) Consensus clustering cumulative distribution function (CDF) for k=2 to 9; (B) relative change in area under CDF curve for k=2 to 9; (C) The ESCC cohort from TCGA was divided into two distinct clusters when k=2; (D) distribution of each sample when k ranges from 2 to 9; (E) comparison of the relationship between the clinicopathological characteristics of two clusters.