Fig. 6. JNK inhibitor strengthens the inhibitory effects of SH on ROS and inflammation in CS-induced MLE-15 cells. (A) The protein expression of p-JNKJNK was measured by Western blot. (B and C) The levels of ROS and MDA in MLE-15 cells. (D) The levels of TNF-α, IL-1β, and IL-6 in MLE-15 cells were measured by ELISA kits. ^*p<0.05 vs. Control group, ^†p<0.05 vs. CS group, ^‡p<0.05 vs. CS+SH group. The dose of SH was 100 mM. SH, sodium houttuyfonate; CS, cell stretch; ROS, reactive oxygen species; MDA, malonaldehyde.