Skip to main content
. 2021 May 12;11:563126. doi: 10.3389/fcimb.2021.563126

Table 1.

lncRNAs as potential biomarker for sepsis and sepsis-induced organ dysfunctions.

lncRNA Sepsis patients/healthy controls Diagnosis value of sepsis (AUC) Prognostic value of mortality (AUC) sample level Ref
lncRNA ZFAS1 202/200 0.814 0.628 plasma down (Xu and Shao, 2019)
lncRNA NEAT1 59/56 0.851 - peripheral blood mononuclear cells up (Huang et al., 2017)
lncRNA NEAT1 152/150 0.730 0.641 plasma up (Huang et al., 2018)
lncRNA NEAT1/miR-124 axis 82/82 0.829 0.830 plasma up (He et al., 2019)
lncRNA MALAT1 120/60 0.910 0.886 plasma up (Chen et al., 2020)
lncRNA MALAT1 190/190 0.823 0.755 plasma up (Geng et al., 2019)
lncRNA MALAT1/miR-125a 196/196 0.931 0.678 plasma up (Liu et al., 2020)
lncRNA ITSN1-2 309/300 0.777 0.654 plasma up (Zeng et al., 2019)
lnc-MEG3/miR-21 axis 219/219 0.934 0.669 plasma up (Na et al., 2020)
lncRNA ANRIL 126/125 0.843 0.785 plasma up (Gui et al., 2019)
lncRNA Sepsis patients Diagnosis value of organ dysfunctions (AUC) Prognostic value of mortality (AUC) sample level Ref
Lung
lncRNA MALAT1 152 0.674 0.651 plasma up (Huang and Zhao, 2019)
Lnc-THRIL 109 0.706 0.780 plasma up (Wang et al., 2019)
Kidney
lncRNA TCONS_00016233 192 0.894 - plasma up (Zhang et al., 2020)