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. 2021 May 12;11:524851. doi: 10.3389/fcimb.2021.524851

Table 3.

Densities of enteroendocrine cells in the duodenum of controls, total IBS group, PI-IBS, and idiopathic IBS patients before and after receiving FMT.

Hormone Enteroendocrine cell densities (cells/mm2) Pa-value Pb-value Pc-value Pd-value Pe-value Pf-value Pg-value Ph-value Pi-value
Control, n = 12 Total IBS,Before, n = 12 Total IBS,After, n = 12 PI-IBS, before, n = 6 PI-IBS, after, n = 6 Idiopathic IBS, before, n = 6 Idiopathic IBS, after, n = 6
Chromogranin A 228 ± 33.6 370.3 ± 21 269.8 ± 22 340.8 ± 34 422.7 ± 31 399.8 ± 20.9 316.8 ± 10.2 0.0099 0.0133 0.2 0.006 0.005 0.4 0.98 0.0006 0.0065
Secretin 74 ± 3.8 83.8 ± 4.9 86.7 ± 5.9 80.5 ± 8.8 89.7 ± 10.7 87.2 ± 4.8 83.7 ± 5.9 0.32 0.21 0.99 0.5 0.1 0.3 0.5 0.099 0.6
Cholecystokinin 80 ± 4.7 122.8 ± 6.7 110.7 ± 8.1 113 ± 10.4 126.5 ± 0.5 132.5 ± 7.2 94.8 ± 9 0.0007 0.023 0.055 0.005 0.0008 0.5 0.2 0.052 0.0006
Gastric inhibitory peptide 53.3 ± 5.7 65.1 ± 3.8 70.3 ± 6.2 60 ± 3 ± 3.7 84 ± 7.1 69.8 ± 6.3 57.2 ± 7 0.33 0.19 0.96 0.01 0.2 0.99 0.5 0.014 0.2
Serotonin 76.5 ± 13.6 135.1 ± 14.7 142 ± 12.8 100.5 ± 7.1 160.7 ± 16.6 169.7 ± 20.6 123.3 ± 17.3 0.04 0.0088 0.7 0.005 0.01 0.2 0.7 0.012 0.034
Somatostatin 42.3 ± 5.6 58.6 ± 4 66.2 ± 6.3 52.3 ± 2.7 78.5 ± 8.1 64.8 ± 7 53.8 ± 6.8 0.033 0.012 0.3 0.006 0.03 0.3 0.3 0.011 0.017

Data are presented as the mean ± SEM. Comparison: Kruskal–Wallis with Dunn’s post test, acontrols vs. total IBS patients before FMT, bcontrols vs. total IBS patients after FMT, ccontrols vs. PI IBS patients before FMT, dcontrols vs. PI IBS patients after FMT, econtrols vs. idiopathic IBS patients before FMT, fcontrols vs. idiopathic IBS patients after FMT; and Paired t test, gtotal IBS patients before vs. after FMT, hPI-IBS patients before vs. after FMT, IIdiopathic IBS patients before vs. after FMT. FMT, fecal microbiota transplantation; IBS, irritable bowel syndrome; PI, post-infectious.

The bolded numbers are significant values <0.05.