Table 1.
Correlation between miR-103a-3p or miR-10a-5p expression and Clinical and biochemical characteristics of patient with IVF-ET treatment.
Variables | N | miR-103a-3p | P-value | miR-10a-5p | P-value | |
---|---|---|---|---|---|---|
(total = 106) | Median (Q1–Q3) | Median (Q1–Q3) | ||||
Maternal age (years) | <37 | 77 | 8.00 (5.08-10.84) | 0.913 | 1.89 (0.75-3.04) | 0.962 |
≥37 | 29 | 8.83 (3.65-12.11) | 1.62 (0.77-3.08) | |||
BMI (kg/m2) | <18.5 | 4 | 8.74 (5.49-10.90) | 0.488 | 2.27 (0.90-3.57) | 0.777 |
18.5≤BMI<25 | 70 | 8.42 (4.96-11.45) | 1.80 (0.64-3.00) | |||
≥25 | 32 | 5.73 (3.11-11.98) | 1.94 (1.14-3.15) | |||
FSH (IU/l) | <10 | 89 | 7.56 (4.21-10.54) | 0.079 | 1.50 (0.75-2.71) | 0.003 |
≥10 | 17 | 11.7 (6.42-14.97) | 3.93 (1.97-4.31) | |||
LH (IU/l) | ≤4 | 58 | 7.55 (3.82-9.39) | 0.03 | 1.08 (0.55-2.18) | <0.001 |
<4 | 48 | 9.66 (5.56-13.22) | 2.93 (1.41-3.75) | |||
E2 (pg/ml) | ≤45 | 52 | 8.34 (4.15-11.97) | 0.48 | 1.37 (0.57-2.91) | 0.118 |
<45 | 54 | 7.62 (4.47-11.28) | 2.12 (1.07-3.16) | |||
T (pg/ml) | ≤30 | 102 | 7.92 (4.47-11.32) | 0.459 | 1.66 (0.73-2.92) | 0.02 |
<30 | 4 | 8.90 (4.47-40.71) | 3.52 (2.77-4.11) | |||
AMH (ng/ml) | <2 | 31 | 9.11 (4.54-12.28) | 0.256 | 2.14 (1.09-3.29) | 0.196 |
≥2 | 75 | 7.70 (4.27-11.06) | 1.62 (0.57-2.97) | |||
P4 (ng/ml) | ≤4 | 96 | 7.85 (4.34-11.19) | 0.271 | 1.66 (0.70-2.95) | 0.205 |
<4 | 10 | 9.51 (6.68-13.80) | 2.74 (1.09-3.62) | |||
Diagnosis | Primary infertility | 66 | 8.30 (4.79-11.69) | 0.772 | 2.07 (1.08-3.93) | 0.128 |
Secondary infertility | 40 | 7.62 (3.79-11.28) | 1.44 (0.54-2.70) |
Median (Q1–Q3), median (25th - 75th percentiles). BMI, body mass index; FSH, follicle-stimulating hormone; LH, luteinizing hormone; E2,17β-estradiol; T, testosterone; AMH, anti-Müllerian hormone; AFC, antral follicle count. Values of miRNAs are calculated by 2 -ΔCt ×1000, ΔCT = Raw Ct (miRNA) -Raw Ct (U6).