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. 2021 May 12;12:679492. doi: 10.3389/fendo.2021.679492

Figure 1.

Figure 1

Effect of aging upon glucose and insulin tolerance. (A) Blood glucose and (B) its AUC before (0 min) and 15, 30, 60 and 120 min after 1g × kg-1 intraperitoneal glucose administration (ipGTT, n = 10 CTL and 10 OLD). (C) Blood glucose and (D) its AUC before (0 min) and 5, 10, 15, 20, 25, 30 and 60 min after 0.75U × kg-1 intraperitoneal insulin administration (ipITT, n = 9 CTL and 9 OLD). CTL, 3-month-old mice; and OLD, 18-month-old mice. Data are presented as the mean ± standard deviation (SD). Student’s unpaired t-test was used to compare the groups (*p ≤ 0.05 vs CTL).