Table 6.

Visual acuity in left eye and right eye over time and their cross-sectional and longitudinal correlations (Pearson Correlation) among eyes with AMD category 3 at baseline in the AREDS participants (N = 1463 participants, 871 bilateral, and 592 unilateral).

		Time points (Months)
		0	12	24	36	48	60
Left eye	Mean (SD) VA score	83.6 (5.8)	82.8 (7.2)	81.4 (9.2)	80.0 (11.2)	78.6 (12.7)	76.7 (15.0)
Right eye	Mean (SD) VA score	84.0 (5.7)	82.7 (7.7)	81.5 (10.1)	79.7 (12.6)	78.1 (14.7)	76.3 (16.5)
		Pearson Correlation Coefficient
Left eye	0 (N = 1156)	1.00	0.42	0.33	0.30	0.29	0.26
	12 (N = 1104)		1.00	0.74	0.63	0.56	0.51
	24 (N = 1056)			1.00	0.81	0.72	0.63
	36 (N = 1031)				1.00	0.79	0.71
	48 (N = 996)					1.00	0.85
	60 (N = 953)						1.00
Right eye	0 (N = 1178)	1.00	0.39	0.34	0.29	0.26	0.26
	12 (N = 1122)		1.00	0.73	0.58	0.56	0.52
	24 (N = 1086)			1.00	0.80	0.75	0.70
	36 (N = 1061)				1.00	0.85	0.80
	48 (N = 1024)					1.00	0.90
	60 (N = 979)						1.00
Combined	0 (N = 2334)	1.00	0.40	0.33	0.29	0.27	0.26
	12 (N = 2226)		1.00	0.73	0.60	0.56	0.52
	24 (N = 2142)			1.00	0.81	0.74	0.67
	36 (N = 2092)				1.00	0.82	0.76
	48 (N = 2020)					1.00	0.88
	60 (N = 1932)						1.00
Inter-eye correlation	Pearson ρ	0.48	0.34	0.26	0.29	0.33	0.35
	N of bilateral subjects	871	832	797	777	746	715