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. Author manuscript; available in PMC: 2021 May 26.
Published in final edited form as: Ophthalmic Epidemiol. 2020 Aug 2;28(1):3–20. doi: 10.1080/09286586.2020.1786590

Table 8.

Visual acuity in left eye and right eye over time and their cross-sectional and longitudinal correlations (Pearson Correlation) among randomly selected 200 participants in eyes with AMD category 3 at baseline in the AREDS (200 participants, 114 bilateral, 86 unilateral).

Time points (Months)
0 12 24 36 48 60
Left eye Mean (SD) VA score 83.5 (6.2) 82.2 (7.7) 81.1 (10.3) 80.1 (11.0) 79.9 (10.2) 78.0 (12.0)
Right eye Mean (SD) VA score 83.6 (5.6) 82.9 (7.1) 81.9 (10.2) 80.5 (11.5) 77.6 (16.3) 76.2 (18.4)
Left eye Pearson Correlation Coefficient
  0 (N = 161)   1.00   0.34   0.20   0.23   0.33   0.29
12 (N = 155)   1.00   0.63   0.59   0.52   0.48
24 (N = 145)   1.00   0.76   0.69   0.56
36 (N = 144)   1.00   0.76   0.64
48 (N = 134)   1.00   0.89
60 (N = 131)   1.00
Right eye
  0 (N = 153)   1.00   0.42   0.30   0.30   0.26   0.25
12 (N = 149)   1.00   0.69   0.59   0.50   0.44
24 (N = 137)   1.00   0.86   0.67   0.58
36 (N = 136)   1.00   0.79   0.69
48 (N = 129)   1.00   0.91
60 (N = 126)   1.00
Combined
  0 (N = 314)   1.00   0.38   0.25   0.27   0.27   0.26
12 (N = 304)   1.00   0.66   0.59   0.49   0.44
24 (N = 282)   1.00   0.81   0.67   0.57
36 (N = 280)   1.00   0.77   0.67
48 (N = 263)   1.00   0.90
60 (N = 257)   1.00
Inter-eye correlation Pearson ρ   0.49   0.23   0.23   0.20   0.40   0.44
N of bilateral subjects 114 111 101 101 94 92