Table 8.
Visual acuity in left eye and right eye over time and their cross-sectional and longitudinal correlations (Pearson Correlation) among randomly selected 200 participants in eyes with AMD category 3 at baseline in the AREDS (200 participants, 114 bilateral, 86 unilateral).
| Time points (Months) |
|||||||
|---|---|---|---|---|---|---|---|
| 0 | 12 | 24 | 36 | 48 | 60 | ||
| Left eye | Mean (SD) VA score | 83.5 (6.2) | 82.2 (7.7) | 81.1 (10.3) | 80.1 (11.0) | 79.9 (10.2) | 78.0 (12.0) |
| Right eye | Mean (SD) VA score | 83.6 (5.6) | 82.9 (7.1) | 81.9 (10.2) | 80.5 (11.5) | 77.6 (16.3) | 76.2 (18.4) |
| Left eye | Pearson Correlation Coefficient | ||||||
| 0 (N = 161) | 1.00 | 0.34 | 0.20 | 0.23 | 0.33 | 0.29 | |
| 12 (N = 155) | 1.00 | 0.63 | 0.59 | 0.52 | 0.48 | ||
| 24 (N = 145) | 1.00 | 0.76 | 0.69 | 0.56 | |||
| 36 (N = 144) | 1.00 | 0.76 | 0.64 | ||||
| 48 (N = 134) | 1.00 | 0.89 | |||||
| 60 (N = 131) | 1.00 | ||||||
| Right eye | |||||||
| 0 (N = 153) | 1.00 | 0.42 | 0.30 | 0.30 | 0.26 | 0.25 | |
| 12 (N = 149) | 1.00 | 0.69 | 0.59 | 0.50 | 0.44 | ||
| 24 (N = 137) | 1.00 | 0.86 | 0.67 | 0.58 | |||
| 36 (N = 136) | 1.00 | 0.79 | 0.69 | ||||
| 48 (N = 129) | 1.00 | 0.91 | |||||
| 60 (N = 126) | 1.00 | ||||||
| Combined | |||||||
| 0 (N = 314) | 1.00 | 0.38 | 0.25 | 0.27 | 0.27 | 0.26 | |
| 12 (N = 304) | 1.00 | 0.66 | 0.59 | 0.49 | 0.44 | ||
| 24 (N = 282) | 1.00 | 0.81 | 0.67 | 0.57 | |||
| 36 (N = 280) | 1.00 | 0.77 | 0.67 | ||||
| 48 (N = 263) | 1.00 | 0.90 | |||||
| 60 (N = 257) | 1.00 | ||||||
| Inter-eye correlation | Pearson ρ | 0.49 | 0.23 | 0.23 | 0.20 | 0.40 | 0.44 |
| N of bilateral subjects | 114 | 111 | 101 | 101 | 94 | 92 | |