Scope of the enantioselective oxygenation of 3-benzylquinolone derivatives 2 catalysed by the chiral manganese porphyrin catalyst 1.

Entrya	2	X	R	3 b [%]	% eec
1	2a	H	4′-Me	60 (80)	96
2	2b	H	3′-Me	58 (82)	99
3	2c	H	2′-Me	64 (92)	97
4	2d	H	3′,4′-Me2	59 (68)	92
5	2e	H	H	61 (84)	95
6	2f	H	4′-OMe	53 (74)	93
7	2g	H	4′-F	53 (60)	91
8	2h	H	4′-Cl	18 (62)	98
9	2i	H	3′-CF3	26 (54)	92
10	2j	6-Me	4′-Me	60 (71)	98
11	2k	7-Me	4′-Me	53 (65)	96

^aAll reactions were conducted at a iodosobenzene concentration of 10 mM in dichloromethane employing 1.0 equiv. of PhIO (60 μmol), 3.0 equiv. of 2 (180 μmol) and 1.5 mol% of 1 (0.9 μmol).

^bAll yields refer to isolated material. Yields in brackets are based on reisolated starting material 2.

^cEnantiomeric excess (% ee) as determined by HPLC analysis on a chiral stationary phase.