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Study flow diagram. RNC = reduced nicotine content; UNC = usual nicotine content Due to limited availability of SPECTRUM UNC menthol cigarettes, 51 menthol smokers used comparable nicotine level SPECTRUM menthol cigarettes during Usual Nicotine Content Baseline and continued using this dose if they were randomized to the UNC group. Nicotine contents are based on an estimated 0.7 g tobacco content per cigarette and nicotine concentrations (mg/g) from Richter et al.21
