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. 2021 Jan 14;70(2):145–160. doi: 10.1538/expanim.20-0158

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©2021 Japanese Association for Laboratory Animal Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

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Fig. 1. — Genealogy of the C57BL/6 substrains. Dates and relationships are derived from the vendors’ websites and Mekada et al. (2009 and 2015) [6, 7]. Abbreviations: J, The Jackson Laboratory (JAX); Jcl, CLEA Japan, Inc.; Jms, Institute of Medical Science, Japan; Slc, Japan SLC, Inc.; Ms, National Institute of Genetics; Ei, Dr. Eva M. Eicher; Lac, Laboratory Animal Centre (MRC Carshalton Lab Animal Centre); Ola, Olac, Ltd.; Hsd, Harlan Sprague-Dawley, Inc.; CSAL, Centre de Sélection des Animaux de Laboratoire; Rj, Centre D’Elevage R. Janvier; Rcc, RCC Ltd.; Han, Zentralinstitut fur Versuchstierzucht, Hannover; M&B A/S, Taconic’s Bomholtgard, Denmark, facility; Tac, Taconic Biosciences, Inc.; Nrs, National Institute for Quantum and of Radiological Science and Technology; N, National Institutes of Health; Hla, Hilltop Lab Animals, Inc.; Jic, Central Institute for Experimental Animals, Japan; Cr, NCI, DCTD Animal Production Program; Sim, Simonsen Laboratories, Inc.; Crl, Charles River Laboratories; Crlj, Charles River Laboratories Japan; Seac, Seac Yoshitomi, Ltd. (Kyodo Co., Ltd.); By, Dr. Donald W. Bailey. *Derived from embryos frozen in 1984.