Table 2.
The comparison of serum cytokine levels of patients with idiopathic granulomatous mastitis and healthy controls.
| Cytokines | IGM (n = 11) | HC (n = 7) | p-Value | ||
|---|---|---|---|---|---|
| Median (IQR) | Median (IQR) | ||||
| TNF-α, pg/mL | 11.66 | (8.70−24.11) | 7.21 | (4.97−7.21) | <0.001 |
| IL-1β, pg/mL | 2.80 | (1.59−3.52) | 0.21 | (N.D.−1.42) | <0.001 |
| IL-2, pg/mL | 13.77 | (3.97−22.08) | 2.63 | (N.D.−6.97) | 0.023 |
| IL-4, pg/mL | N.D. | N.D. | N.A. | ||
| IL-6, pg/mL | 3.89 | (N.D.−6.09) | N.D. | 0.023 | |
| IL-10, pg/mL | 1.13 | (0.55−1.59) | 1.06 | (0.81−1.99) | 0.892 |
| IL-12p70, pg/mL | 6.39 | (6.24−6.98) | 6.10 | (5.95−6.10) | 0.016 |
| IL-17A, pg/mL | 1.13 | (0.41−1.98) | N.D. | 0.041 | |
| IL-22, pg/mL | N.D. | (N.D.−14.29) | N.D. | (N.D.−48.66) | 0.885 |
| IL-23, pg/mL | N.D. | N.D. | N.A. | ||
| GM-CSF, pg/mL | N.D. | (N.D.−3.52) | N.D. | 0.118 | |
IGM, idiopathic granulomatous mastitis; HC, healthy controls; IQR, interquartile range; TNF, tumor necrosis factor; IL, interleukin; N.D., not detectable; N.A., not applicable; GM-CSF, granulocyte–macrophage colony-stimulating factor.