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. 2021 May 12;13(10):2314. doi: 10.3390/cancers13102314

Figure 3.

Figure 3

CDDP treatment increases the expression of Orai3 in both NSCLC cell lines. Orai3 gene expression following CDDP treatment in A549 cells (A-a). Western blot representing Orai3 protein expression (A-b) with its respective quantification normalized to Tubulin (A-c), ANOVA followed by Dunnett post-test ** p <0.01, * p < 0.05 of at least three independent experiments. Orai3 expression at mRNA level under CDDP treatment in H23 cells (B-a), ANOVA followed by Dunnett post-test *** p < 0.001 of three independent experiments. Western blot representing Orai3 protein expression (B-b) with its respective quantification normalized to Tubulin (B-c), ANOVA followed by Dunnett post-test ** p < 0.01, * p < 0.05, N = 3. (C,D) Orai1 mRNA quantification in A549 (C) and H23 (D) cells treated by CDDP. ANOVA followed by Dunnett post-test ** p < 0.01, N = 4.