Figure 2.

Skeletal muscle cell proliferation activities of phlorotannins isolated from E. cava. Cell viability of six phlorotannins and DHT on C2C12 myoblasts (a), Cell proliferation activity of five phlorotannins, which exhibit non-cytotoxicity on C2C12 myocytes (b), and Creatine kinase activity of DK, PHB, and PPB, which has cell proliferative effects (c). Experiments were performed in triplicate and the data were expressed as mean ± S.E.M.; * p < 0.05, and ** p < 0.01 as compared to the non-treated cells. DK, Dieckol; PHB, 2,7″-phloroglucinol-6,6′-bieckol; PFFA; Phlorofucofuroeckol A; 6,6-BK; 6,6′-bieckol; PPB; Pyrogallol-phloroglucinol-6,6′-bieckol; PG, Phloroglucinol.