Table 4.

Experimental and kinetic data on the hydrolysis of substituted α-hydroxybenzylphosphonates (43).

Entry	Y	R	Yield (%)	tr (h)	k1 (h−1)	k2 (h−1)
1	H	Me	80	6.5	2.64	0.60
2	NO2	Me	82	2.5	5.18	1.24
3	Cl	Me	90	5.5	3.36	0.79
4	F	Me	85	6.0	3.93	0.67
5	CF3	Me	80	5.5	2.03	0.61
6	Me	Me	79	8	1.64	0.31
7	H	Et	82	9.5	1.03	0.35
8	NO2	Et	92	5.5	1.40	0.61
9	Cl	Et	87	8.0	1.08	0.42
10	F	Et	83	9.0	1.35	0.31