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Rescue of LM-induced chemoresistance by PSC833 and SB203580. A549 cells cultured with LM were pre-treated with vehicle (dimethyl sulfoxide), 10 μM of PSC833, or 10 μM of SB203580 for 24 h. Then, the cells were incubated with CDDP and DXR at the concentration indicated for 24 h. Cell injury was measured using the Premix WST-1 Cell Proliferation Assay System. n = 6–8. ** p < 0.01 compared with vehicle. NS, p > 0.05.
