Table 3.
sTF/FIX Assays Between THA and TKA.
| Pre | Day 1b | Day 1a | Day 4 | Day 8 | Day 15 | ||
|---|---|---|---|---|---|---|---|
| 2nd Derivative Peak Time (sec) | THA | 51.2 (46.8-55.2) | 54.2 (48.2-59.7) | 72.3 (67.7-84.4) | 74.1 (67.8-84.0) | 74.0 (66.3-85.2) | 58.7 (53.8-67.4) |
| P | NS | NS | <0.05 | NS | NS | NS | |
| TKA | 51.9 (48.2-56.3) | 56.5 (51.3-59.9) | 81.9 (73.0-87.5) | 73.7 (67.3-81.7) | 71.4 (66.6-77.8) | 60.9 (56.0-67.7) | |
| 2nd Derivative Peak Height (mm Absorbance) |
PRP | 115 (91.1-152) | 132 (101-174) | 109 (83.3-133) | 183 (140-239) | 137 (102-181) | 139 (101-203) |
| P | NS | NS | NS | <0.05 | NS | NS | |
| PPP | 120 (79.8-149) | 117 (88.9-117) | 101 (68.7-119) | 154 (101-194) | 128 (96.2-165) | 123 (93.0-160) | |
| 1st Derivative Peak Time (sec) | PRP | 62.2 (57.1-67.3) | 66.5 (59.4-73.0) | 85.1 (77.6-97.1) | 85.5 (80.4-128) | 85.4 (77.6-98.8) | 69.8 (64.8-81.1) |
| P | NS | NS | <0.05 | NS | NS | NS | |
| PPP | 63.5 (57.4-67.8) | 69.2 (63.1-75.1) | 92.0 (86.6-101) | 88.2 (78.7-99.4) | 84.0 (79.0-93.8) | 72.2 (67.3-79.6) | |
| 1st Derivative Peak Height (mm Absorbance) | PRP | 147 (117-178) | 182 (145-205) | 200 (160-235) | 330 (274-381) | 265 (209-300) | 214 (179-261) |
| P | NS | NS | NS | NS | NS | <0.001 | |
| PPP | 146 (118-170) | 168 (143-193) | 174 (151-218) | 288 (237-362) | 256 (221-279) | 197 (156-220) | |
| Fibrin Formation Time (sec) | PRP | 62.3 (57.9-67.1) | 67.3 (60.6-73.7) | 85.4 (77.7-97.9) | 86.9 (81.0-100) | 85.2 (76.2-97.7) | 69.4 (64.7-80.3) |
| P | NS | NS | <0.05 | NS | NS | NS | |
| PPP | 63.7 (57.7-68.3) | 71.0 (63.7-75.8) | 93.6 (87.3-103) | 89.4 (79.7-101) | 83.6 (80.0-91.1) | 71.5 (67.5-78.6) | |
| Fibrin Formation Height (mm Absorbance) | PRP | 322 (288-365) | 329 (286-377) | 427 (374-470) | 678 (611-739) | 582 (510-642) | 485 (417-549) |
| P | NS | NS | NS | NS | NS | <0.001 | |
| PPP | 322 (283-357) | 347 (300-372) | 414 (366-491) | 633 (585-715) | 551 (520-651) | 468 (394-568) |
Abbreviations: PRP, platelet-rich plasma; PPP, platelet-poor plasma; NS, not significant; THA, total hip arthroplasty; TKA, total knee arthroplasty; sTF/FIX, small tissue factor induced FIX activation.