5-FU	5-Fluoruracil
Ang	Angiopoietin
CAFs	Cancer-associated fibroblasts
CCL	Chemokine ligand
CDK	Cyclin-dependent kinase
CPT-11	Irinotecan
CRC	Colorectal cancer
CRLM	Colorectal liver metastasis
CTL	Cytotoxic T-lymphocyte
CTLA-4	Cytotoxic T-lymphocyte antigen-4
DBD	DNA-binding domain
DFS	Disease-free survival
dMMR	Deficient mismatch repair
dTMP	Deoxythymidine monophosphate
ECM	Extracellular matrix
EGFR	Epidermal growth factor receptor
FAP	Fibroblast activation protein
FdUMP	Fluorodeoxyuridine monophosphate
FP	Fluoropyrimidine
FSP-1	Fibroblast-specific protein, S100A4
GOF	Gain-of-function
HAI	Hepatic arterial infusion
HDI	Human Development Index
HMG-CoA reductase	3-hydroxy-3-methylglutaryl coenzyme A reductase
Hsp	Heat shock protein
ICI	Immune checkpoint inhibitor
LOF	Loss-of-function
LV	Leucovorin
mCRC	Metastatic CRC
MDM2	E3 ubiquitin-protein ligase Mdm2
MHC I	Major histocompatibility complex
micro RNA	miRNA
MMP	Metalloproteinases
MSI-H	High microsatellite instability
MSS/I	Microsatellite stable/instable
NF-κB	Nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells
OS	Overall survival
OX	Oxaliplatin
PD-1	Programmed death-1
PDGFR α/β	Platelet derived growth factor receptor-alpha/beta
PD-L1	Programmed death ligand 1
pMMR	Proficient mismatch repair
POLR2A	DNA-directed RNA polymerase II subunit RPB1
PUMA	P53 Upregulated Modulator of Apoptosis
ROS	Reactive oxygen species
siRNA	silencing RNA
SREBP	Sterol regulatory element-binding protein
TAMs	Tumor-associated macrophages
TCR	T-cell receptor
TME	Tumor microenvironment
Tregs	Regulatory T cells
TNF-α	Tumor necrosis factor-alpha
TS	Thymidylate synthase
UICC	Union for International Cancer Control
VEGF	Vascular endothelial growth factor
wt	Wild-type
ZMC-1	Zinc metallochaperone-1
α-SMA	α-smooth muscle actin