Table 1.

Correlation of agrin expression with clinicopathological features in patients with cholangiocarcinoma.

Variables	Tumor agrin expression		P a
	Low	High
Age			0.084
≤50 years	35	47
>50 years	46	34
Sex			<0.001
Male	33	56
Female	48	25
PVTT	11	42	<0.001
Tumor size			<0.001
≤5 cm	68	33
>5 cm	13	48
Tumor number			0.038
Single	27	41
Multiple	54	40
CA199 > 37 kU/L	68	58	0.088
CEA > 5 ng/mL	37	34	0.751
GGT > 50 U/L	64	56	0.209
Histopathologic grade			0.090
Well + moderately differentiated	31	20
Poorly differentiated	50	61

^aStatistical analyses were performed using the chi-squared test.

PVTT, portal vein tumor thrombus; CEA, carcinoembryonic antigen; GGT, gamma-glutamyltransferase.