Table 2.
Agrin expression is an independent predictive factor for prognosis.
| Variables |
Cumulative recurrence |
Overall survival |
||
|---|---|---|---|---|
| HR (95% CI) | P a | HR (95% CI) | P a | |
| Age (years) | ||||
| ≥50 vs. <50 | 0.63 (0.42–0.95) | 0.028 | 0.84 (0.54–1.31) | 0.436 |
| Sex | ||||
| Male vs. female | 1.42 (0.98–2.07) | 0.065 | 1.06 (0.87–1.29) | 0.543 |
| PVTT | ||||
| Present vs. absent | 0.98 (0.68–1.41) | 0.895 | ||
| Tumor number | ||||
| Multiple vs. single | 0.84 (0.51–1.36) | 0.476 | ||
| Histopathologic grade | ||||
| Well + moderately differentiated vs. poorly differentiated | 1.66 (1.07–2.59) | 0.025 | 1.18 (0.73–1.92) | 0.491 |
| Tumor size | ||||
| >5 cm vs. ≤5 cm | 0.88 (0.59–1.33) | 0.567 | ||
| Agrin expression | ||||
| High vs. low | 2.65 (1.79–3.89) | <0.001 | 2.47 (1.63–3.75) | <0.001 |
aCox proportional hazards regression. PVTT, portal vein tumor thrombus; HR, hazard ratio; CI, confidence interval.