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Expression of glutamate-decarboxylase (GAD67) and glutaminase in 9-month-old Tg4-42 +/+ mice. Quantitative GAD67 expression in cortex (CTX) (a) and caudate putamen (CPu) (b) and glutaminase expression in cortex (c) and caudate putamen (d) shown as immunoreactive (IR) area in percent. Representative images of NTG and Tg4-42 +/+ brain sections. Scale bar 100μm for all images. (a-d) n = 7 per group. Mean + SEM. Unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001.
