Fig. 6.

Quantification of Aβ₄₂ expression in the central nervous system of Tg4-42 +/+ mice. Histological quantification of Aβ₄₂ expression in cortex (a), caudate putamen (b), and hippocampus (c) in 9-month-old Tg4-42 +/+ mice. d) Representative images of Aβ₄₂ (green) and DAPI (blue) labeling in 9-month-old Tg4-42 +/+ and non-transgenic mice. e) Biochemical quantification of cortical total human Aβ₄₂ levels in pg/mg and (f) soluble human Aβ₄₂ levels in pg/mg. (a-f) n = 7 per group. Mean + SEM. Unpaired t-test. ^***p < 0.001.