Table 1.
Demographic characteristics of the sample
| Variable | Level | Median (IQR) or n (%) | |||
| All (n = 238,195) | General dementia (n = 4259) | ADem (1531) | VaD (669) | ||
| Age | 60.9 (9.1) | 65.5 (5.8) | 65.9 (5.3) | 66.3 (4.7) | |
| Sex | Female | 129,034 (54.2) | 1,939 (45.5) | 795 (51.9) | 267 (39.9) |
| Male | 109,161 (45.8) | 2,320 (54.5) | 736 (48.1) | 402 (60.1) | |
| Education | Graduate degree | 72,385 (30.7) | 947 (22.6) | 313 (20.9) | 115 (17.6) |
| No graduate degree | 163,563 (69.3) | 3,235 (77.4) | 1,199 (79.1) | 539 (82.4) | |
| Deprivation | –2.5 (3.6) | –2.2 (4.2) | –2.3 (4.1) | –2.2 (3.8) | |
| Alcohol consumption | Daily or almost daily | 54,261 (22.8) | 990 (23.3) | 311 (20.3) | 152 (22.8) |
| 3 or 4 times a week | 57,255 (24.1) | 814 (19.1) | 313 (20.5) | 117 (17.5) | |
| 1 or 2 times a week | 60,106 (25.2) | 952 (22.4) | 357 (23.3) | 147 (22.0) | |
| 1–3 times a month | 24,778 (10.4) | 396 (9.3) | 156 (10.2) | 59 (8.8) | |
| Special occasions only | 25,409 (10.7) | 576 (13.5) | 215 (14.1) | 91 (13.6) | |
| Never | 16,239 (6.8) | 524 (12.3) | 177 (11.6) | 101 (15.1) | |
| Smoking | Current smoker | 21,470 (9.0) | 413 (9.8) | 115 (7.6) | 74 (11.2) |
| Previous smoker | 89,608 (37.8) | 1,839 (43.4) | 647 (42.6) | 310 (46.8) | |
| Non-smoker | 126,288 (53.2) | 1,983 (46.8) | 757 (49.8) | 278 (42.0) | |
| Physical activity | Strenuous | 19,441 (8.7) | 186 (4.9) | 74 (5.2) | 27 (4.7) |
| Moderate | 148,812 (66.6) | 2,350 (62.1) | 908 (64.2) | 359 (62.2) | |
| Light | 55,137 (24.7) | 1,247 (33.0) | 432 (30.6) | 191 (28.6) | |
| BMI | 26.8 (5.7) | 27.1 (6.0) | 26.8 (5.6) | 27.8 (7.1) | |
| APOE variant | ɛ2 | 30,818 (13.3) | 306 (8.2) | 79 (5.3) | 51 (7.8) |
| ɛ3 | 138,634 (59.7) | 1,559 (42.0) | 505 (33.6) | 275 (42.1) | |
| ɛ4 | 62,665 (27.0) | 1,846 (49.7) | 917 (61.1) | 327 (50.1) | |