Table 2.
Grade of Fibrosis | Modified Scale |
---|---|
0 | Alveolar Septa: No fibrotic burden at the flimsiest small fibers in some alveolar walls Lung structure: Normal lung |
1 | Alveolar Septa: Isolated gentle fibrotic changes (septum ≤3× thicker than normal) Lung structure: Alveoli partly enlarged and rarefied, but no fibrotic masses present. |
2 | Alveolar Septa: Clearly fibrotic changes (septum >3× thicker than normal) with not-like formation but not connected to each other Lung structure: Alveoli partly enlarged and rarefied, but no fibrotic masses. |
3 | Alveolar Septa: Contiguous fibrotic walls (septum >3× thicker than normal) predominantly in whole microscopic field Lung structure: Alveoli partly enlarged and rarefied, but no fibrotic masses. |
4 | Alveolar Septa: Variable Lung structure: Single fibrotic masses (≤10% microscopic field) |
5 | Alveolar Septa: Variable Lung structure: Confluent fibrotic masses (>10% and ≤50% of microscopic field). Lung structure severely damaged but still preserved. |
6 | Alveolar Septa: Variable, most not existent Lung structure: Large contiguous fibrotic masses (>50% of microscopic field). Lung architecture mostly not preserved. |
7 | Alveolar Septa: Non-existent Lung structure: Alveoli nearly obliterated with fibrous masses but still up to five air bubbles. |
8 | Alveolar Septa: Non-existent Lung structure: Microscopic field with complete obliteration with fibrotic masses. |