Table 5.
Hematological parameters of the animals submitted to the experiment.
| Hematological Parameters | Sham | Vehicle | EOCW (mg/kg) | DFC | Reference Range * | ||
|---|---|---|---|---|---|---|---|
| 50 | 100 | 200 | |||||
| Total leukocytes (×103/µL) | 4.7 ± 0.6 a | 3.1 ± 1.2 b | 5.0 ± 0.3 a | 4.5 ± 0.6 a | 6.1 ± 1.4 a | 3.6 ± 0.4 b | 2.3−9.9 |
| Red blood cells (×103/µL) | 8.0 ± 1.0 a | 5.8 ± 0.7 b | 6.1 ± 1.7 b | 6.1 ± 0.9 b | 7.6 ± 1.2 a | 9.0 ± 0.4 a | 5.2−8.8 |
| Hematocrit (%) | 51.8 ±1.9 a | 38.4 ± 4.0 b | 40.5 ± 0.70 b | 39.2 ± 1.70 b | 46.0 ± 2.4 a | 52.8 ± 2.9 a | 27.2–48.5 |
| Hemoglobin (g/dL) | 15.7 ± 0.9 | 13.7 ± 1.7 | 13.6 ± 0.9 | 13. 9 ± 0.8 | 14.6 ± 1.0 | 16.0 ± 0.8 | 11.1–17.1 |
| Platelets (×103/µL) | 1.0 ± 0.2 | 1.3 ± 0.7 | 1.0 ± 0.4 | 1.2 ± 0.2 | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.76–1.31 |
* Reference range values available in Lima et al. (2014) [32]. Different letters (a, b) in the same line express significantly different values between them (ANOVA and multiple comparison Tukey’s test, p < 0.05).