Table 1.
Demographics and disease characteristics of the study subjects used for nano-LC-ESI-MS/MS analysis.
| Characteristics | Healthy Subjects (HPTotal) | Ovarian Cancer Patients (OCTotal) | ||||
|---|---|---|---|---|---|---|
| HPwt
(N = 10) |
HPvar
(N = 10) |
p-Value | OCwt
(N = 10) |
OCvar
(N = 10) |
p-Value | |
| Age (mean ± SD) | 42 ± 10.4 | 32 ± 14.5 | 0.116 | 59 ± 6.7 | 57 ± 9.1 | 0.622 |
| Concurrent cancer | 1.0 | 0.032 | ||||
| Yes (n) | 0 | 0 | 0 | 5 | ||
| No (n) | 10 | 10 | 10 | 5 | ||
| Family history | <0.001 | 1.0 | ||||
| Yes (n) | 0 | 10 | 0 | 1 | ||
| No (n) | 10 | 0 | 10 | 9 | ||
| OC stage | 1.0 | |||||
| II | NA | NA | 1 | 0 | ||
| III | NA | NA | 8 | 9 | ||
| IV | NA | NA | 1 | 1 | ||
| BRCA variant | 1.0 | 0.650 | ||||
| BRCA1 | NA | 5 | NA | 3 | ||
| BRCA2 | NA | 5 | NA | 7 | ||
| Ovarian histopathology | 1.0 | |||||
| High-grade serous carcinoma | NA | NA | 10 | 10 | ||
| Preoperative CA125 level (mean ± SD) | NA | NA | 3167 ± 5910.9 | 1662 ± 1793.7 | 0.451 | |
| Preoperative platelet level (mean + SD) | NA | NA | 323 ± 157.9 | 308 ± 215.3 | 0.855 | |
NA: not applicable, SD: standard deviation. All results are reported as a mean (SD) or percentage (%), with p-values appropriately calculated using the Mann–Whitney U test or Fisher’s exact test.