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. 2021 May 12;21(10):3358. doi: 10.3390/s21103358

Table 1.

Comparison of performance of HRP-based LFIAs for the detection of IgG (for reference, conventional AuNP-based LFIAs and ELISAs for IgG are also reported as the first and last table entries, respectively).

Technique Detection Principle Tracer Limit of Detection Reference
Colorimetric LFIA Visual detection AuNP 50 ng mL−1 [72]
Colorimetric LFIA Measurement of color intensity with a portable strip reader AuNP 2 ng mL−1 [72]
Colorimetric LFIA Visual detection HRP with metal enhancer (AuNPs) using TMB substrate 5 ng mL−1 [72]
Colorimetric LFIA Measurement of color intensity with a portable strip reader HRP with metal enhancer (AuNPs) using TMB substrate 200 pg mL−1 [72]
Colorimetric LFIA Visual detection HRP with metal enhancer (AuNPs) using AEC substrate 5 ng mL−1 [72]
Colorimetric LFIA Measurement of color intensity with a portable strip reader HRP with metal enhancer (AuNPs) using AEC substrate 310 pg mL−1 [72]
Colorimetric LFIA Visual detection HRP with metal enhancer (AuNPs) using DAB substrate 50 ng mL−1 [72]
Colorimetric LFIA Measurement of color intensity with a portable strip reader HRP with metal enhancer (AuNPs) using DAB substrate 1.6 ng mL−1 [72]
Colorimetric ELISA Measurements of absorbance using a microwell plate reader HRP using TMB substrate 0.24 ng mL−1 [78]
Colorimetric ELISA Measurements of absorbance using a microwell plate reader HRP using TMB substrate 20 pg mL−1 [79]