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. 2021 May 12;9(5):495. doi: 10.3390/vaccines9050495

Figure 7.

Figure 7

Neutrophil count and cytokines/chemokines in blood of STm challenged mice. C57BL/6 mice were immunized with STmGMMA/Alhydrogel by the SC route at weeks 0 and 10, and IV challenged with STm at week 12. Mice were sacrificed 24 h after infection. As control, two groups received saline administration and the first was challenged with STm, while the other was left unchallenged. (A) Neutrophil population in blood identified as CD45+CD11b+Ly6G+ cells by multiparametric flow cytometry analysis. Symbols represent individual mice and bars indicate the mean ± SEM of 6 or 7 mice per group. Unpaired Mann-Whitney test was used to assess statistical difference between groups. ** p ≤ 0.01. (B) Fold change of cytokine/chemokine concentration detected in mice challenged with STm compared with mice immunized with STmGMMA/Alhydrogel and then infected. Data are reported as arithmetic mean of 6 animals for each group.