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. 2021 May 12;8(5):22. doi: 10.3390/medicines8050022

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Influence of quercetin on the induction of nasal allergy-like symptoms in OVA-sensitized mice after the nasal antigenic challenge. OVA-sensitized BALB/c mice were treated orally with various doses of quercetin once a day for five consecutive days before OVA nasal provocation. Nasal allergy-like symptoms, namely the number of sneezes (A) and nasal rubbing movements (B), were counted for 10 min just after nasal antigenic provocation. The data are expressed as the mean ± SE of five mice. OVA: ovalbumin; Nor. Cont.: normal control; IS: intraperitoneal sensitization alone; NC: nasal challenge alone; and N.S.: not significant (p > 0.05) vs. IS + NC, quercetin (0 mg/kg). * Significant (p < 0.05) vs. Nor. C. ** Significant (p < 0.05) vs. IS + NC, quercetin (0 mg/kg).