Table 3.

Experimental design for SWE procedure and obtained contents of polyphenolic compounds analyzed by HPLC.

Experimental Design (BBD)				Compound (mg/g of Peels)
Run	Temperature (°C)	Time (min)	Solvent-Solid Ratio (mL/g)	5-HMF	Hesperidin	Narirutin	Rutin	Chlorogenic Acid
1.	175	10	20	4.68	9.28	3.65	3.14	0.27
2.	175	15	10	4.32	8.56	1.05	0.89	1.90
3.	130	10	30	0.01	9.19	3.83	1.31	0.28
4.	220	5	20	10.08	0.19	0.09	0.19	58.93
5.	175	15	30	9.48	14.89	4.27	3.91	8.69
6.	175	10	20	6.48	10.52	3.63	3.03	3.62
7.	220	10	10	5.38	1.15	0.03	0.80	21.26
8.	130	15	20	0.00	11.25	4.87	1.04	0.00
9.	130	10	10	0.00	3.66	1.99	0.52	0.08
10.	175	5	30	7.83	15.07	4.72	4.21	0.28
11.	175	5	10	3.67	5.28	1.91	1.68	0.79
12.	175	10	20	6.18	9.61	3.44	2.94	1.98
13.	175	10	20	6.02	11.23	3.38	2.81	1.84
14.	220	15	20	6.39	0.16	0.08	0.18	54.48
15.	130	5	20	0.03	7.34	3.76	1.04	0.29
16.	175	10	20	6.41	11.99	5.11	4.27	9.10
17.	220	10	30	14.33	0.35	0.11	0.26	68.58