Table 1.
Parameter | Native | Dilution 20% | Dilution 40% |
p-Value Native vs. 20% |
p-Value Native vs. 40% |
---|---|---|---|---|---|
INTEM CT (s) | 220 (214–255) | 196.5 (180–207.3) | 250 (236–268.8) | 0.11 | 0.57 |
INTEM CFT (s) | 173 (147–186) | 196.5 (153.3–235.8) | 462.5 (414.3–593.3) | 0.16 | <0.01 |
INTEM MCF (mm) | 52 (50–53) | 45.5 (42.3–47.8) | 30 (29–32.5) | 0.12 | 0.01 |
INTEM LI60 (%) | 99 (98–100) | 97 (96–99) | 95 (95–99) | 0.71 | 0.28 |
EXTEM CT (s) | 92 (67–102) | 72.5 (66.3–94) | 119 (88.3–125.8) | 0.55 | 0.55 |
EXTEM CFT (s) | 160 (119–242) | 213.5 (203.3–255) | 388 (367–434) | 0.29 | 0.29 |
EXTEM MCF (mm) | 51 (46–58) | 46.5 (45.3–47.8) | 35.5 (34.3–36.8) | 0.03 | 0.01 |
EXTEM LI60 (%) | 100 (97.5–100) | 99 (96.8–100) | 99 (96–100) | 1.0 | 1.0 |
FIBTEM CT (s) | 71 (59–86) | 63.5 (58.5–87.5) | 265 (130–570) | 0.81 | 0.05 |
FIBTEM MCF (mm) | 10 (9–12) | 7 (6.3–7.8) | 3 (2–3.8) | 0.06 | <0.01 |
FIBTEM LI60 (%) | 100 (100) | 100 (100) | 100 (100) | n.c. | 1.0 |
APTEM CT (s) | 67 (63–83) | 70.5 (64.5–79.3) | 100 (89–145) | 0.86 | 0.02 |
APTEM CFT (s) | 175 (146–236) | 226 (201.3–264.5) | 413 (325–455) | 0.57 | 0.29 |
APTEM MCF (mm) | 49 (46–52) | 46 (42.3–47.8) | 40 (35–40) | 0.48 | 0.22 |
APTEM LI60 (%) | 100 (100) | 99 (97.3–100) | 100 (97–100) | 0.56 | 1.0 |
Shown p-values represent either the differences between the native reconstituted blood and the 20% dilution and 40% dilution, respectively. Significant differences are highlighted in italics and bold. Abbreviations: CT = clotting time; CFT = clot formation time; LI60 = lysis index after 60 min; MCF = mean clot firmness; n.c. = not calculable).