Table 2.
Treatment of blood samples that were diluted by 20% and treated either with fibrinogen or combined fibrinogen/FXIII.
| Parameter | Dilution 20% | Dilution 20% Fibrinogen |
Dilution 20% Fibrinogen + FXIII |
p-Value Dilution 20% vs. Fibrinogen |
p-Value Dilution 20% vs. Fibrinogen + FXIII |
p-Value Dilution 20% Fibrinogen vs. Fibrinogen + FXIII |
|---|---|---|---|---|---|---|
| INTEM CT (s) | 196.5 (180–207.3) | 224 (211.5–267.5) | 213.5 (203–246.5) | 0.19 | 0.19 | 0.49 |
| INTEM CFT (s) | 196.5 (153.3–235.8) | 155 (128.5–182.5) | 140 (114.5–194.8) | 0.08 | 0.16 | 0.77 |
| INTEM MCF (mm) | 45.5 (42.3–47.8) | 49.5 (46.3–53.8) | 51 (44.8–54.8) | 0.04 | 0.12 | 0.34 |
| INTEM LI60 (%) | 97 (96–99) | 99 (98–99) | 100 (99.8–100) | 0.30 | 0.30 | 0.37 |
| EXTEM CT (s) | 72.5 (66.3–94) | 54 (50.3–57.3) | 51 (45.5–53.5) | 0.03 | 0.06 | 0.36 |
| EXTEM CFT (s) | 213.5 (203.3–255) | 175 (136.5–217.3) | 141.5 (117.3–192.5) | 0.04 | 0.04 | 0.11 |
| EXTEM MCF (mm) | 46.5 (45.3–47.8) | 50.5 (48.3–54.8) | 53 (48.3–55.8) | 0.02 | 0.02 | 0.36 |
| EXTEM LI60 (%) | 99 (96.8–100) | 100 (100) | 100 (100) | 0.09 | 0.09 | n.c. |
| FIBTEM CT (s) | 63.5 (58.5–87.5) | 48.5 (46.5–50) | 50.5 (43–57) | 0.65 | 0.04 | 0.84 |
| FIBTEM MCF (mm) | 7 (6.3–7.8) | 13.5 (13–17.3) | 16.5 (15.3–18.8) | <0.01 | <0.01 | 0.1 |
| FIBTEM LI60 (%) | 100 (100) | 100 (100) | 100 (100) | n.c. | n.c. | n.c. |
| APTEM CT (s) | 70.5 (64.5–79.3) | 53 (51–59) | 49 (48.3–52.8) | 0.02 | 0.02 | 0.81 |
| APTEM CFT (s) | 226 (201.3–264.5) | 191 (119–219) | 132.5 (93–176) | 0.01 | <0.01 | 0.01 |
| APTEM MCF (mm) | 46 (42.3–47.8) | 50 (49–55) | 56.5 (51.8–60.8) | 0.03 | 0.01 | 0.01 |
| APTEM LI60 (%) | 99 (97.3–100) | 100 (99.5–100) | 100 (100) | 0.09 | 0.09 | 1.0 |
Significant differences are highlighted in italics and bold. Abbreviations: CT = Clotting Time; CFT = Clot Formation Time; LI60 = lysis index after 60 min; MCF = mean clot firmness; n.c. = not calculable.