Table 2.
Overview of the infection status of Mastomys following inoculation or exposure with Morogoro virus (MORV) or Mobala virus (MOBV).
| Blood | Urine | Organs | |||
|---|---|---|---|---|---|
| Group | Sampling Period (Weeks Post-Birth) | PCR Positive Samples/Tested Samples 1 per Sampling Period |
Ab Positive Samples/Tested Samples 1 per Sampling Period |
PCR Positive Samples/Tested Samples 1 per Sampling Period |
Virus Positive Animals/Tested Animals 2 per Sampling Period |
| MORV inoculation day 2 (n = 5) | 1 | 1/1 | 0/1 | 1/1 | 1/1 |
| 2 | 1/1 | 1/1 | n.t. | 1/1 | |
| 4–6 | 9/9 | 9/9 | 3/3 | n.t. | |
| 7–9 | 8/8 | 7/8 | 1/1 | n.t. | |
| 10–12 | 8/8 | 8/8 | n.t. | n.t. | |
| 13–15 | 8/8 | 8/8 | n.t. | n.t. | |
| 20–22 | 3/3 | 3/3 | n.t. | 3/3 | |
| MORV inoculation day 6 (n = 15) | 2 | 4/4 | 0/4 | n.t. | 4/4 |
| 3 | 4/4 | 4/4 | n.t. | 4/4 | |
| 4 | 4/4 | 4/4 | n.t. | 3/4 | |
| 5 | 3/3 | 3/3 | n.t. | 2/3 | |
| MORV inoculation day 14 (n = 10) | 3 | 4/4 | 1/4 | n.t. | 4/4 |
| 4 | 2/3 | 3/3 | n.t. | 0/3 | |
| 5 | 2/3 | 3/3 | n.t. | n.t. | |
| MORV inoculation day 27 (n = 10) | 5 | 0/2 | 1/2 | n.t. | 0/2 |
| 6 | 0/2 | 1/2 | n.t. | n.t. | |
| 7 | 0/2 | 2/2 | n.t. | n.t. | |
| 8 | 0/2 | 2/2 | n.t. | 0/2 | |
| 9 | 1/2 | 2/2 | n.t. | n.t. | |
| MORV exposure to persistently infected inviduals from birth (n = 37) | 0–1 | 6/10 | 8/10 | 4/9 | 5/12 |
| 2–3 | 10/14 | 14/14 | 6/8 | 6/8 | |
| 4–7 | 26/32 | 31/32 | 2/4 | 0/4 | |
| 8–10 | 14/20 | 20/20 | 2/3 | 4/5 | |
| 16–20 | 2/6 | 6/6 | n.t. | 2/5 | |
| MORV exposure to persistently infected inviduals from day 25 (n = 9) | 4–5 | 7/9 | 2/9 | n.t. | n.t. |
| 6–7 | 5/18 | 18/18 | 0/3 | n.t. | |
| 8 | 0/9 | 9/9 | 0/7 | 0/3 | |
| MORV exposure of adults to infected individuals (n = 14) | 0–1 | 0/10 | 3/10 | n.t. | n.t. |
| 2–4 | 3/15 | 9/15 | n.t. | 0/1 | |
| 5–9 | 1/8 | 8/8 | n.t. | 0/2 | |
| 11–13 | 0/2 | 2/2 | n.t. | 0/2 | |
| MOBV inoculation day 2 (n = 4) | 1 | 1/1 | 0/1 | 1/1 | 0/1 |
| 2 | 1/1 | 1/1 | 1/1 | 1/1 | |
| 4–7 | 0/6 | 6/6 | 0/4 | n.t. | |
| 8–10 | 0/6 | 6/6 | 0/2 | 0/2 | |
| MOBV exposure to infected individuals from birth (n = 12) | 1–4 | 0/12 | 0/8 | n.t. | 0/4 |
| 5–7 | 0/8 | 0/8 | n.t. | n.t. | |
| MOBV exposure of adults to infected individuals (n = 2) | 1–2 | 0/3 | 0/3 | n.t. | n.t. |
| 5–10 | 0/3 | 0/3 | n.t. | n.t. | |
1 For blood and urine, the number of positive samples versus the total number of samples tested during a given time period is shown. Since individuals were sampled up to 3 times per sampling period, the number of tested samples can exceed the number of animals per group. 2 For organs, the number of positive animals versus the total number of tested animals is shown. Animals were considered positive, if one or more of the tested organs contained infectious virus. n.t. = not tested.