Table 3.
Clustering of annotated pathways (enrichment score 3.64).
| Knowledgebase | Annotated Pathway/Term | EASE Score (p Value) |
|---|---|---|
| INTERPRO | CXC chemokine | 2.2 × 10−7 |
| INTERPRO | CXC chemokine, conserved site | 2.2 × 10−7 |
| INTERPRO | chemokine interleukin-8-like domain | 1.1 × 10−5 |
| SMART | SCY | 1.6 × 10−5 |
| GOTERM_MF_DIRECT | chemokine activity | 1.8 × 10−5 |
| UP_KEYWORDS | cytokine | 1.9 × 10−5 |
| UP_KEYWORDS | disulfide bond | 2.8 × 10−5 |
| GOTERM_MF_DIRECT | CXCR chemokine receptor binding | 3.8 × 10−5 |
| GOTERM_BP_DIRECT | cell chemotaxis | 4.3 × 10−5 |
| GOTERM_BP_DIRECT | chemokine-mediated signaling pathway | 5.6 × 10−5 |
| UP_KEYWORDS | secreted | 1.2 × 10−4 |
| KEGG_PATHWAY | salmonella infection | 1.9 × 10−4 |
| UP_SEQ_FEATURE | signal peptide | 2.0 × 10−4 |
| GOTERM_BP_DIRECT | positive regulation of neutrophil chemotaxis | 2.5 × 10−4 |
| KEGG_PATHWAY | cytokine-cytokine receptor interaction | 2.7 × 10−4 |
| GOTERM_BP_DIRECT | chemotaxis | 2.8 × 10−4 |
| GOTERM_CC_DIRECT | extracellular region | 5.5 × 10−4 |
| GOTERM_BP_DIRECT | inflammatory response | 6.1 × 10−4 |
| GOTERM_BP_DIRECT | response to lipopolysaccharide | 6.7 × 10−4 |
| GOTERM_BP_DIRECT | immune response | 9.0 × 10−4 |
| UP_KEYWORDS | signal | 9.9 × 10−4 |
| GOTERM_CC_DIRECT | extracellular space | 1.4 × 10−3 |
| KEGG_PATHWAY | chemokine signaling pathway | 2.0 × 10−3 |
| KEGG_PATHWAY | legionellosis | 2.6 × 10−3 |
| KEGG_PATHWAY | NOD-like receptor signaling pathway | 2.8 × 10−3 |
| UP_KEYWORDS | chemotaxis | 3.2 × 10−3 |
| KEGG_PATHWAY | rheumatoid arthritis | 6.8 × 10−3 |
| UP_KEYWORDS | inflammatory response | 7.7 × 10−3 |
| KEGG_PATHWAY | TNF signaling pathway | 9.9 × 10−3 |
| UP_SEQ_FEATURE | disulfide bond | 9.9 × 10−3 |