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. 2021 May 12;13(5):706. doi: 10.3390/pharmaceutics13050706

Figure 4.

Figure 4

Differential effects of PLB on inducing A375 and SK-MEL-28 apoptosis. A375 and SK-MEL-28 cells pretreated with DMSO and 1 and 3 µM PLB were stained with Annexin V-FITC and PI. Cells heated at 55 °C for 16 min were the positive controls. (a) Cells with fluorescence were detected by flow cytometry. (b) The percentage of late apoptotic or necrotic and early apoptotic A375 cells in DMSO and 1 and 3 µM PLB groups. (c) The percentage of late apoptotic or necrotic and early apoptotic SK-MEL-28 cells in DMSO and 1 and 3 µM PLB groups. Results are expressed as mean ± SD (n = 3). ** p < 0.01. PI, propidium iodide.