5-HT	5-hydroxytryptamine (serotonin)
ACh	acetylcholine
Ale	alendronate
ANOVA	analysis of variance
Bas	baseline
BP	arterial blood pressure
bpm	beats per minute
Cont	control
Ð	dispersity
D h	hydrodynamic diameter
DLS	dynamic light scattering
D n	number-average diameter
D w	weight-average diameter
FDA	Food and Drug Administration
Fe3O4@PEG-Ale	magnetite coated with poly(ethylene glycol)-alendronate
FTIR	Fourier-transform infrared
HR	heart rate
i.v.	intravenous
KPSS	high concentration of potassium (125 mmol/l)-containing physiological saline solution
L-NAME	N(ω)-nitro-L-arginine methyl ester
MAP	mean arterial pressure
M n	number-average molar mass
M w	weight-average molar mass
MRI	magnetic resonance imaging
NMR	nuclear magnetic resonance
NO	nitric oxide
NOS	nitric oxide synthase
NPs	nanoparticles
PB	phosphate buffer
PD	polydispersity
PEG	poly(ethylene glycol)
PEG-NHS	α-methoxy poly(ethylene glycol) succinimidyl ester
PSS	physiological saline solution
RBC	red blood cell
SEM	standard error of mean
SHR	spontaneously hypertensive rat
SNP	sodium nitroprusside
TEM	transmission electron microscope
TGA	thermogravimetric analysis
WKY	Wistar-Kyoto rat
ZFC-FC	zero-field-cooled and field-cooled