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. 2021 May 9;10(5):752. doi: 10.3390/antiox10050752

Figure 1.

Figure 1

Possible pathophysiological mechanisms responsible for adverse outcomes during COVID-19 infection in patients with type 1 diabetes. ARDS: acute respiratory distress syndrome; ACE2: angiotensin converting enzyme 2; DKA: diabetic ketoacidosis; NET: neutrophil extracellular trap; NLRP3: NOD-like receptor family pyrin domain-containing 3; ROS: reactive oxygen species; Th: T-helper; Tregs: regulatory T-cells; WBC: white blood cells.