Figure 2.

The fitted curve for patient presentation time against serum venom among patients who developed wound necrosis and their clinical information. (1) Cases on the left bottom belong to case Group I (early and mild presentation). No tissue necrosis developed in this group. (2) Cases on the left side of the 6-h line are Group II patients. Patients who presented early and with worse local manifestations. Six of them did not develop wound necrosis. Five cases on the upper left (within the circle) had high serum venom levels but did not develop necrosis after antivenom administration. However, three of them, including one case that did not receive antivenom, developed wound necrosis. The necrotic lesions may occur as early as 4–6 h after the snakebite. (3) Most of the Group III cases who presented late developed tissue necrosis despite antivenom treatment. They had low serum venom levels.