Table 8.
Polyunsaturated fatty acids (PUFA) content in the PL fraction (nmol/g of wet tissue) in the red gastrocnemius muscle in the control (standard diet) and high-fat diet (HFD) groups after two-week cannabidiol (CBD) treatment.
| Fatty Acid | Control | CBD | HFD | HFD + CBD |
|---|---|---|---|---|
| (18:2n6c) | 6016.99 ± 705.69 | 7281.82 ±495.03 * | 6140.77 ± 331.08 | 7653.15 ± 440.06 *,# |
| (20:4n6) | 3922.92 ± 371.42 | 4684.31 ±184.04 * | 4765.12 ± 384.66 * | 6019.30 ± 184.80 *,# |
| (18:3n3) | 71.94 ± 7.37 | 79.89 ± 2.95 * | 41.45 ± 4.01 * | 48.43 ± 6.68 *,# |
| (20:5n3) | 58.99 ± 5.93 | 54.48 ± 4.28 | 41.21 ± 3.97 * | 43.74 ± 2.36 * |
| (22:6n3) | 2283.89 ± 382.17 | 3793.13 ±419.76 * | 3052.58 ± 291.44 * | 4341.88 ± 260.71 *,# |
| n-6 PUFAs | 9939.90 ± 907.86 | 11,884.97 ± 503.74 * | 11,008.32 ± 512.03 * | 13,672.45 ± 592.99 *,# |
| n-3 PUFAs | 2419.60 ± 397.65 | 3857.01 ± 450.31 * | 3140.37 ± 286.37 * | 4471.28 ± 250.34 *,# |
The data are expressed as mean values ± SD, n = 10 in each group. * p < 0.05 indicates a significant difference: the control group vs. the examined group in the red gastrocnemius muscle; # p < 0.05 indicates a significant difference: HFD vs. HFD + CBD in the red gastrocnemius muscle; 18:2n6c (linoleic acid, LA); 20:4n6 (arachidonic acid, AA); 18:3n3 (α-linolenic acid, ALA); 20:5n3 (eicosapentaenoic acid, EPA); 22:6n3 (docosahexaenoic acid, DHA).