DCM |
Diabetic cardiomyopathy |
DPP-4 |
Dipeptidyl peptidase-4 |
GLP-1 |
Glucagon-like peptide-1 |
SGLT2 |
Sodium-dependent glucose transporter-2 |
AE |
Aglycone equivalent |
ESC |
European Society of Cardiology |
ROS |
Reactive oxygen species |
AGE |
Advanced glycation end products |
PKC |
Protein kinase C |
DAG |
Diacylglycerol |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
MAPK |
Mitogen-activated protein kinase |
ERK |
Extracellular-regulated kinase |
JNK |
c-Jun N-terminal kinase |
SOD |
Superoxide dismutase |
H2O2
|
Hydrogen peroxide |
RAGE |
Receptor for AGE |
Keap1 |
Kelch-like ECH-associated protein |
IL |
Interleukin |
SIRT-1 |
Sirtuin-1 |
TLR-4 |
Toll-like receptor 4 |
TGF-β |
Tumor growth factor β |
Nrf2 |
Nuclear erythroid 2-related factor 2 |
CTGF |
Connective tissue growth factor |
iNOS |
Inducible nitric oxide synthase |
TNF-α |
Tumor necrosis factor-α |
ASK1 |
Apoptosis signal-regulating kinase 1 |
FOXO1 |
Forkhead box protein O1 |
NQO1 |
NADPH dehydrogenase |
MnSOD |
Manganese SOD |
HO-1 |
Heme oxygenase-1 |
SGLT1 |
Sodium-dependent glucose transporter 1 |
AMPK-mTOR |
AMP-activated serine/threonine protein kinase- mammalian target-of-rapamycin |