Table 1.
Characteristics of micro- and nanoparticles, hepatitis C trapping systems and virus-mimicking nanoparticles.
| System | Polymer Particles | Protein for Immobilization | Characteristics of Neat Polymer Particles (in PBS) | Characteristics of Modified Polymer Particles (in PBS) | |||||
|---|---|---|---|---|---|---|---|---|---|
| DH, nm | PDI | ζ-Potential | DH, nm | PDI | ζ-Potential | Amount of Bound Protein, µg/mg of Particles | |||
| Microtraps | PLA | LEL CD81-SA-Cy3 | 800 | 0.39 | −34 | 850 | 0.26 | −68 | 3 |
| 1640 | 0.37 | −38 | 1860 | 0.28 | −48 | 2 | |||
| Negative control | PLA | SBTI-Cy3 | 800 | 0.39 | −34 | 860 | 0.23 | −75 | 2.5 |
| Nanotraps | PEG-b-PLA | LEL CD81-SA-Cy3 | 90 | 0.05 | −24 | 105 | 0.29 | −43 | 15 |
| HC VMPs | PEG-b-PLA | E2-GFP | 90 | 0.05 | −24 | 85 | 0.19 | −35 | 15 |