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. 2021 May 11;11(5):1356. doi: 10.3390/ani11051356

Table 6.

Effects of different forms of zinc oxide on the blood profiles of weaned piglets (n = 20).

Zn, Status, and Level CON ZnO Chelate
-ZnO
Nano
-ZnO
SE p-Value
Items 0 2500 200 200 trt
WBC, 103/μL 27.5 20.1 23.5 23.0 2.4 0.253
RBC, 106/μL 7.9 7.8 8.2 7.9 0.3 0.806
Lymphocyte, % 73.4 62.9 62.2 61.5 3.7 0.160
Monocyte, % 0.5 0.6 2.15 0.6 0.4 0.461
Neutrophil, % 23.7 24.7 31.0 37.6 3.0 0.518
IgG, mg/dL 189.0 229.0 191.0 219.0 13.0 0.128
IgM, mg/dL 19.3 20.0 19.3 23.0 2.6 0.663
Zinc, ug/dL y,z 164.9 b 235.5 a 165.3 b 175.8 b 9.6 0.007

Abbreviation: CON, no additional added zinc oxide in diet (negative control); ZnO, CON + 2500 ppm zinc oxide (positive control); chelate-ZnO, CON + zinc chelate; nano-ZnO, CON + nanoparticle size of zinc; SE, standard error; RBC, red blood cell; WBC, white blood cell; IgG, immunogloblin G; IgM, immunogloblin M. a,b Means within a row with different letters are significantly different at p < 0.05. y contrast: ZnO vs. chelate-ZnO (p < 0.05). z contrast: ZnO vs. nano- ZnO (p < 0.05).