Table 3.

Effect of F16-betulin on the activity of complexes of the electron transport chain of liver mitochondria (expressed in percentage vs control).

	Complex I	Complex II	Complex III	Complex IV
10 µM conjugate	99.76 ± 3.74	89.51 ± 1.09 *	112.97 ± 3.31 *	103.49 ± 3.02
20 µM conjugate	62.27 ± 1.76 *	85.68 ± 3.04 *	124.66 ± 1.37 *	91.83 ± 3.77

In the absence of conjugate (control), the activities of electron transport chain (ETC) complexes I, II, III and IV were 381 ± 13, 424 ± 16, 688 ± 12 and 482 ± 15 nmol/min/mg protein respectively. Redox activity in the absence of F16-betulin was taken as 100%. Table shows means ± SEM (n = 3). * p < 0.05 (vs. control).