Table 14.

Activity of Brazilian propolis on different Leishmania infection models.

Propolis Origin	Substances	Infection Model	Activity	Ref.
Brazil	Nitric oxide	L. braziliensis-infected mice	The combination of propolis (5 mg/kg) with NO favored the healing, collagen synthesis, the function of macrophages and fibroblasts, reduced expression of proinflammatory and tissue damage markers	[152]
Brazil (green propolis)	Liposomal meglumine antimoniate	L. infantum-infected mice	Reduced the parasitic burden in the liver, without damaging kidney, liver, spleen, and heart (500 mg/kg)	[153]