Skip to main content
. 2021 May 12;13(5):701. doi: 10.3390/pharmaceutics13050701

Table 6.

Geometry and role of the materials used to build polymeric implants.

Materials Design of the Device Drug Role of the Materials References
EVA-PVA Reservoir surrounded by a membrane Glancicovir EVA: membrane to limit the surface area for the permeability of the medication
PVA: frame that regulates the rate of drug permeability
[8,9,14,15,16,17,18]
PVA-Silicone Tablet geometry FA PVA: suture tab and coating
Silicone: coating
[16,17,33,34,35,36,37,38,39]
PVA Cylinder FA PVA: caps to regulate drug release rate [40]
PVA-PMMA-Silicone Ring Avastin PVA: polymeric carrier to control release and stability of the drug
PMMA: reservoir material
Silicone: check valves for refilling
[41]
Titanium-PVA-EVA Helix TA Titanium-PVA-EVA: reservoir [14,42]
PU-CNPs-PCL DXM PU: base material
CNPs: as additive to modify mechanical properties
PCL: as soft segment to improve polymer degradation, biocompatibility and stability
[57]
PI-PVA-Silicone Tubular - PI: base material
PVA: membrane
Silicone: adhesive plug
[63]
PCL - TA, 5-FU, DXM PCL: carrier [80,81,82]
PLA Disc TA PLA: base material [92]
PLGA-HPMC Rod DXM PLGA-HPMC: base material [35,108,109,110]